The essential role of the 3' terminal template base in the first steps of protein-primed DNA replication.

Bacteriophages ϕ29 and Nf from Bacillus subtilis start replication of their linear genomes at both ends using a protein-primed mechanism by means of which the DNA polymerase initiates replication by adding dAMP to the terminal protein, this insertion being directed by the second and third 3' te...

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Bibliographic Details
Main Authors: Irene Rodríguez, Elisa Longás, Miguel de Vega, Margarita Salas
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3480470?pdf=render