Functional Diversification of Motor Neuron-specific Isl1 Enhancers during Evolution.
Functional diversification of motor neurons has occurred in order to selectively control the movements of different body parts including head, trunk and limbs. Here we report that transcription of Isl1, a major gene necessary for motor neuron identity, is controlled by two enhancers, CREST1 (E1) and...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2015-10-01
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Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC4598079?pdf=render |