Transcriptional network analysis identifies key elements governing the recombinant protein production provoked reprogramming of carbon and energy metabolism in Escherichia coli BL21 (DE3)

Abstract The impact of recombinant protein production on carbon and energy metabolism in Escherichia coli BL21 (DE3) was studied through transcriptome and proteome analysis of cells induced in carbon‐limited fed‐batch cultures during either fast or slow growth. Production of human basic fibroblast g...

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Bibliographic Details
Main Authors: Zhaopeng Li, Robert Geffers, Garima Jain, Frank Klawonn, Öznur Kökpinar, Manfred Nimtz, Wolfgang Schmidt‐Heck, Ursula Rinas
Format: Article
Language:English
Published: Wiley 2021-09-01
Series:Engineering Reports
Subjects:
Online Access:https://doi.org/10.1002/eng2.12393