AWD regulates timed activation of BMP signaling in intestinal stem cells to maintain tissue homeostasis

AWD regulates timed activation of BMP signaling in intestinal stem cells to maintain tissue homeostasis

Regeneration after injury in the Drosophila intestine involves early activation of intestinal stem cells (ISCs) and subsequent return to quiescence. Here the authors show that return to quiescence by ISCs involves BMP Type I receptor Tkv protein stabilization along with AWD mediated internalization...

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Bibliographic Details
Main Authors: Xiaoyu Tracy Cai, Hongjie Li, Abu Safyan, Jennifer Gawlik, George Pyrowolakis, Heinrich Jasper
Format: Article
Language:English
Published: Nature Publishing Group 2019-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-10926-2

Internet

https://doi.org/10.1038/s41467-019-10926-2

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