Shenmai Injection Protects Against Doxorubicin-Induced Cardiotoxicity via Maintaining Mitochondrial Homeostasis

Shenmai Injection Protects Against Doxorubicin-Induced Cardiotoxicity via Maintaining Mitochondrial Homeostasis

Shenmai injection (SMI), as a patented traditional Chinese medicine, is extracted from Panax ginseng and Ophiopogon japonicus. It commonly used in the treatment of cardiovascular disease and in the control of cardiac toxicity induced by doxorubicin (DOX) treatment. However, its anti-cardiotoxicity m...

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Bibliographic Details
Main Authors: Lin Li, Jinghao Li, Qilong Wang, Xin Zhao, Dongli Yang, Lu Niu, Yanze Yang, Xianxian Zheng, Limin Hu, Yuhong Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Pharmacology
Subjects:
doxorubicin
Shenmai injection
cardiotoxicity
PI3K/Akt signaling pathway
AMP-activated protein kinase
mitochondrial dynamics
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.00815/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2020.00815/full

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