Phyla- and subtype-selectivity of CgNa, a Na+ channel toxin from the venom of the Giant Caribbean Sea Anemone Condylactis gigantea
Because of their prominent role in electro-excitability, voltage-gated sodium (NaV) channels have become the foremost important target of animal toxins. These toxins have developed the ability to discriminate between closely related NaV subtypes, making them powerful tools to study NaV channel funct...
Main Authors: | Bert eBillen, Sarah eDebaveye, Lászlo eBéress, Anoland eGarateix, Jan eTytgat |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2010-11-01
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Series: | Frontiers in Pharmacology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fphar.2010.00133/full |
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