Short-lived, transitory cell-cell interactions foster migration-dependent aggregation.

During embryonic development, motile cells aggregate into cohesive groups, which give rise to tissues and organs. The role of cell migration in regulating aggregation is unclear. The current paradigm for aggregation is based on an equilibrium model of differential cell adhesivity to neighboring cell...

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Bibliographic Details
Main Authors: Melissa D Pope, Anand R Asthagiri
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3422298?pdf=render