Inferring interaction partners from protein sequences using mutual information.
Functional protein-protein interactions are crucial in most cellular processes. They enable multi-protein complexes to assemble and to remain stable, and they allow signal transduction in various pathways. Functional interactions between proteins result in coevolution between the interacting partner...
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Format: | Article |
Language: | English |
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Public Library of Science (PLoS)
2018-11-01
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Series: | PLoS Computational Biology |
Online Access: | http://europepmc.org/articles/PMC6258550?pdf=render |