Coevolutionary Analysis Reveals a Conserved Dual Binding Interface between Extracytoplasmic Function σ Factors and Class I Anti-σ Factors

In the bacterial world, extracytoplasmic function σ factors (ECFs) are the most widespread family of alternative σ factors, mediating many cellular responses to environmental cues, such as stress. This work uses a computational approach to investigate how these σ factors interact with class I anti-σ...

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Bibliographic Details
Main Authors: Delia Casas-Pastor, Angelika Diehl, Georg Fritz
Format: Article
Language:English
Published: American Society for Microbiology 2020-08-01
Series:mSystems
Subjects:
Online Access:https://doi.org/10.1128/mSystems.00310-20