HIV-1 Tat and cocaine mediated synaptopathy in cortical and midbrain neurons is prevented by the isoflavone Equol

HIV-1 Tat and cocaine mediated synaptopathy in cortical and midbrain neurons is prevented by the isoflavone Equol

Illicit drugs, such as cocaine, are known to increase the likelihood and severity of HIV-1 associated neurocognitive disorders (HAND). In the current studies synaptic integrity was assessed following exposure to low concentrations of the HIV-1 viral protein Tat 1-86B, with or without cocaine, by qua...

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Bibliographic Details
Main Authors: Sarah eBertrand, Calvin eHu, Marina eAksenova, Charles eMactutus, Rosemarie eBooze
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-09-01
Series:Frontiers in Microbiology
Subjects:
Hand
estrogen receptor
f-actin
S-equol
Soy isoflavone
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.00894/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.00894/full

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