SRC-1 Knockout Exerts No Effect on Amyloid β Deposition in APP/PS1 Mice

Steroid receptor coactivator 1 (SRC-1) is the key coactivator because of its transcriptional activity. Previous studies have shown that SRC-1 is abundant in the hippocampus and has been implicated in cognition. SRC-1 is also related to some major risk factors for Alzheimer’s disease (AD), such as a...

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Bibliographic Details
Main Authors: Qiong Wu, Bin Wang, Qi-Fa Li, Xuan Zhang, Michael Ntim, Xue-Fei Wu, Na Li, Dan-Dan Zhu, Rong Jiang, Jin-Yi Yang, Yu-Hui Yuan, Shao Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Aging Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fnagi.2020.00145/full