Role of carbonic anhydrase IV in the bicarbonate-mediated activation of murine and human sperm.

Role of carbonic anhydrase IV in the bicarbonate-mediated activation of murine and human sperm.

HCO(3) (-) is the signal for early activation of sperm motility. In vivo, this occurs when sperm come into contact with the HCO(3) (-) containing fluids in the reproductive tract. The activated motility enables sperm to travel the long distance to the ovum. In spermatozoa HCO(3) (-) stimulates the a...

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Bibliographic Details
Main Authors: Petra M Wandernoth, Michael Raubuch, Nadja Mannowetz, Holger M Becker, Joachim W Deitmer, William S Sly, Gunther Wennemuth
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2991337?pdf=render

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http://europepmc.org/articles/PMC2991337?pdf=render

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