Isolation and Identification of Cancer Stem-Like Cells in Adenocarcinoma and Squamous Cell Carcinoma of the Lung: A Pilot Study

Isolation and Identification of Cancer Stem-Like Cells in Adenocarcinoma and Squamous Cell Carcinoma of the Lung: A Pilot Study

Background: Lung cancer stem cells (CSCs) share many characteristics with normal stem cells, such as self-renewal and multipotentiality. High expression of aldehyde dehydrogenase (ALDH) has been detected in many tumors, particularly in the CSC compartment, and it plays an important role in tumor pro...

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Bibliographic Details
Main Authors: Valentina Masciale, Giulia Grisendi, Federico Banchelli, Roberto D'Amico, Antonino Maiorana, Pamela Sighinolfi, Alessandro Stefani, Uliano Morandi, Massimo Dominici, Beatrice Aramini
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-12-01
Series:Frontiers in Oncology
Subjects:
cancer stem-like cells
non-small-cell lung cancer
lung adenocarcinoma
lung squamous cell carcinoma
CSC marker
aldehyde dehydrogenase
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.01394/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2019.01394/full

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