Effects of Vitamin D3 on the NADPH Oxidase and Matrix Metalloproteinase 9 in an Animal Model of Global Cerebral Ischemia

Decreased blood flow in the brain leads to a rapid increase in reactive oxygen species (ROS). NADPH oxidase (NOX) is an enzyme family that has the physiological function to produce ROS. NOX2 and NOX4 overexpression is associated with aggravated ischemic injury, while NOX2/4-deficient mice had reduce...

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Main Authors: Milica Velimirović, Gordana Jevtić Dožudić, Vesna Selaković, Tihomir Stojković, Nela Puškaš, Ivan Zaletel, Milica Živković, Vesna Dragutinović, Tatjana Nikolić, Ankica Jelenković, Djordje Djorović, Aleksandar Mirčić, Nataša D. Petronijević
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2018/3273654