Immunomodulatory effects of interferon-γ on human fetal cardiac mesenchymal stromal cells

Immunomodulatory effects of interferon-γ on human fetal cardiac mesenchymal stromal cells

Abstract Background Mesenchymal stromal cells (MSCs), due to their regenerative and immunomodulatory properties, are therapeutically used for diseases, including heart failure. As early gestational-phase embryonic tissues exhibit extraordinary regenerative potential, fetal MSCs exposed to inflammati...

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Bibliographic Details
Main Authors: Karl-Henrik Grinnemo, Marie Löfling, Lubov Nathanson, Roland Baumgartner, Daniel F. J. Ketelhuth, Vladimir Beljanski, Lindsay C. Davies, Cecilia Österholm
Format: Article
Language:English
Published: BMC 2019-12-01
Series:Stem Cell Research & Therapy
Subjects:
Mesenchymal stromal cells
Fetal hearts
ISL1
Inflammation
Immunomodulation
Programmed cell death protein 1
Online Access:https://doi.org/10.1186/s13287-019-1489-1

Internet

https://doi.org/10.1186/s13287-019-1489-1

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