Structural plasticity and conformational transitions of HIV envelope glycoprotein gp120.

HIV envelope glycoproteins undergo large-scale conformational changes as they interact with cellular receptors to cause the fusion of viral and cellular membranes that permits viral entry to infect targeted cells. Conformational dynamics in HIV gp120 are also important in masking conserved receptor...

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Bibliographic Details
Main Authors: Anil Korkut, Wayne A Hendrickson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3531394?pdf=render