Identification of the Key Regulators of Spina Bifida Through Graph-Theoretical Approach

Identification of the Key Regulators of Spina Bifida Through Graph-Theoretical Approach

Spina Bifida (SB) is a congenital spinal cord malformation. Efforts to discern the key regulators (KRs) of the SB protein-protein interaction (PPI) network are requisite for developing its successful interventions. The architecture of the SB network, constructed from 117 manually curated genes was f...

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Bibliographic Details
Main Authors: Naaila Tamkeen, Suliman Yousef AlOmar, Saeed Awad M. Alqahtani, Abdullah Al-jurayyan, Anam Farooqui, Safia Tazyeen, Nadeem Ahmad, Romana Ishrat
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Genetics
Subjects:
Spina bifida
protein-protein interaction network
topological analysis
rich-club analysis
key regulators
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.597983/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2021.597983/full

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