Potentiated serotonin signaling in serotonin re‐uptake transporter knockout mice increases enterocyte mass and small intestinal absorptive function

Potentiated serotonin signaling in serotonin re‐uptake transporter knockout mice increases enterocyte mass and small intestinal absorptive function

Abstract Genetic knockout of the serotonin reuptake transporter (SERT) potentiates serotonin signaling and increases crypt‐cell proliferation, neuroplasticity, and mucosal surface area. However, it remains unknown whether these changes occur throughout the small intestine and whether they increase n...

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Bibliographic Details
Main Authors: Chasen J. Greig, Lucy Zhang, Robert A. Cowles
Format: Article
Language:English
Published: Wiley 2019-11-01
Series:Physiological Reports
Subjects:
Absorptive function
citrulline
intestinal mucosal growth
mouse model
Online Access:https://doi.org/10.14814/phy2.14278

Internet

https://doi.org/10.14814/phy2.14278

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