Development of a core Clostridium thermocellum kinetic metabolic model consistent with multiple genetic perturbations

Development of a core Clostridium thermocellum kinetic metabolic model consistent with multiple genetic perturbations

Abstract Background Clostridium thermocellum is a Gram-positive anaerobe with the ability to hydrolyze and metabolize cellulose into biofuels such as ethanol, making it an attractive candidate for consolidated bioprocessing (CBP). At present, metabolic engineering in C. thermocellum is hindered due...

Full description

Bibliographic Details
Main Authors: Satyakam Dash, Ali Khodayari, Jilai Zhou, Evert K. Holwerda, Daniel G. Olson, Lee R. Lynd, Costas D. Maranas
Format: Article
Language:English
Published: BMC 2017-05-01
Series:Biotechnology for Biofuels
Subjects:
Clostridium thermocellum
Genome-scale metabolic model
Kinetic model
Ensemble modeling
Nitrogen limitation
Ethanol stress
Online Access:http://link.springer.com/article/10.1186/s13068-017-0792-2

Internet

http://link.springer.com/article/10.1186/s13068-017-0792-2

Similar Items