Epigenetic Changes at the <i>Birc5</i> Promoter Induced by YM155 in Synovial Sarcoma
YM155 is an anti-cancer therapy that has advanced into 11 different human clinical trials to treat various cancers. This apoptosis-inducing therapy indirectly affects the protein levels of survivin (gene: <i>Birc5</i>), but the molecular underpinnings of the mechanism remain largely unkn...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2019-03-01
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| Series: | Journal of Clinical Medicine |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2077-0383/8/3/408 |