Ybp2 associates with the central kinetochore of Saccharomyces cerevisiae and mediates proper mitotic progression.
The spindle checkpoint ensures the accurate segregation of chromosomes by monitoring the status of kinetochore attachment to microtubules. Simultaneous mutations in one of several kinetochore and cohesion genes and a spindle checkpoint gene cause a synthetic-lethal or synthetic-sick phenotype. A syn...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2008-02-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC2238814?pdf=render |