The residual innate lymphoid cells in NFIL3-deficient mice support suboptimal maternal adaptations to pregnancy

The residual innate lymphoid cells in NFIL3-deficient mice support suboptimal maternal adaptations to pregnancy

Uterine NK cells (uNK) are innate lymphoid cells (ILC) that populate the uterus and expand during pregnancy, regulating placental development and fetal growth in humans and mice. We have recently characterised the composition of uterine ILCs (uILCs), some of which require the transcription factor NF...

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Bibliographic Details
Main Authors: Selma eBoulenouar, Jean-Marc eDoisne, Amanda eSferruzzi-Perri, Louise M Gaynor, Jens eKieckbusch, Elisa eBalmas, Hong Wa Yung, Shagayegh eJavadzadeh, Lea eVolmer, Delia A Hawkes, Keli ePhillips, Hugh JM Brady, Abigail L Fowden, Graham J Burton, Ashley eMoffett, Francesco eColucci
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-02-01
Series:Frontiers in Immunology
Subjects:
Placenta
Pregnancy
mouse models
lymphocyte subpopulations
Uterine NK cells
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00043/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00043/full

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