Durable Clinical Benefit in Patients with Advanced Cutaneous Melanoma after Discontinuation of Anti-PD-1 Therapies Due to Immune-Related Adverse Events

Introduction. Anti-PD-1 therapies, pembrolizumab and nivolumab, are currently the standard of care for treatment of patients with metastatic melanoma. Treatment is usually continued until toxicity or disease progression. Though these therapies are well tolerated, some patients discontinue them due t...

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Bibliographic Details
Main Authors: Umang Swami, Varun Monga, Aaron D. Bossler, Yousef Zakharia, Mohammed Milhem
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:Journal of Oncology
Online Access:http://dx.doi.org/10.1155/2019/1856594