Enhanced Identification of Novel Potential Variants for Appendicular Lean Mass by Leveraging Pleiotropy With Bone Mineral Density

Enhanced Identification of Novel Potential Variants for Appendicular Lean Mass by Leveraging Pleiotropy With Bone Mineral Density

Strong relationships have been found between appendicular lean mass (ALM) and bone mineral density (BMD). It may be due to a shared genetic basis, termed pleiotropy. By leveraging the pleiotropy with BMD, the aim of this study was to detect more potential genetic variants for ALM. Using the conditio...

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Bibliographic Details
Main Authors: Cheng Peng, Feng Liu, Kuan-Jui Su, Xu Lin, Yu-Qian Song, Jie Shen, Shi-Di Hu, Qiao-Cong Chen, Hui-Hui Yuan, Wen-Xi Li, Chun-Ping Zeng, Hong-Wen Deng, Hui-Ling Lou
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Immunology
Subjects:
appendicular lean mass
bone mineral density
pleiotropy
genome wide association study
novel SNPs
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.643894/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.643894/full

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