Interleukin-1/-33 Signaling Pathways as Therapeutic Targets for Endometriosis

Endometriosis is an estrogen-dependent disease with symptoms of dysmenorrhea, chronic pain, and infertility that affects 6–10% of women of reproductive age. Medical or surgical therapy, such as administration of an anti-gonadotropin or ovarian cystectomy, provide effective pain relief. However, neit...

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Bibliographic Details
Main Authors: Toru Kato, Koubun Yasuda, Kazufumi Matsushita, Ken J. Ishii, Seiichi Hirota, Tomohiro Yoshimoto, Hiroaki Shibahara
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Immunology
Subjects:
ST2
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02021/full