Characterization of chromosome stability in diploid, polyploid and hybrid yeast cells.

Chromosome instability is a key component of cancer progression and many heritable diseases. Understanding why some chromosomes are more unstable than others could provide insight into understanding genome integrity. Here we systematically investigate the spontaneous chromosome loss for all sixteen...

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Bibliographic Details
Main Authors: Rajaraman Kumaran, Shi-Yow Yang, Jun-Yi Leu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3707968?pdf=render