The Differentiation of Rat Oligodendroglial Cells Is Highly Influenced by the Oxygen Tension: In Vitro Model Mimicking Physiologically Normoxic Conditions

The Differentiation of Rat Oligodendroglial Cells Is Highly Influenced by the Oxygen Tension: In Vitro Model Mimicking Physiologically Normoxic Conditions

Oligodendrocyte progenitor cells (OPCs) constitute one of the main populations of dividing cells in the central nervous system (CNS). Physiologically, OPCs give rise to mature, myelinating oligodendrocytes and confer trophic support to their neighboring cells within the nervous tissue. OPCs are know...

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Bibliographic Details
Main Authors: Justyna Janowska, Malgorzata Ziemka-Nalecz, Joanna Sypecka
Format: Article
Language:English
Published: MDPI AG 2018-01-01
Series:International Journal of Molecular Sciences
Subjects:
oligodendrocyte progenitor cells
myelinogenesis
hippocampal organotypic slices
cell proliferation
oligodendrocyte maturation myelin
myelin protein amounts
physiological normoxia
culture density
serum-free culture
Online Access:http://www.mdpi.com/1422-0067/19/2/331

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http://www.mdpi.com/1422-0067/19/2/331

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