Detection of EGFR Gene Mutations in 100 Non-small Cell Lung Cancer Clinical Samples by a Real-time Polymerase Chain Reaction Method Using Amplification Refractory Mutation System Specific Primers and Taqman Fluorescence Probes

Detection of EGFR Gene Mutations in 100 Non-small Cell Lung Cancer Clinical Samples by a Real-time Polymerase Chain Reaction Method Using Amplification Refractory Mutation System Specific Primers and Taqman Fluorescence Probes

Background and objective Epidermal growth factor receptor (EGFR) gene mutation is the most important predictor of the efficiency of EGFR-tyrosine kinase inhibitors in the treatment of non-small cell lung cancer (NSCLC). The detection of EGFR gene mutations can guide individual therapies for NSCLC. N...

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Bibliographic Details
Main Authors: Jing ZHAO, Jinyin ZHAO, Xiao ZHAO, Weijun CHEN, Wei ZHONG, Li ZHANG, Longyun LI, Mengzhao WANG
Format: Article
Language:zho
Published: Chinese Anti-Cancer Association; Chinese Antituberculosis Association 2013-01-01
Series:Chinese Journal of Lung Cancer
Subjects:
Amplification refractory mutation system
Taqman probe
Epidermal growth factor receptor
Mutation detection
Lung neoplasms
Online Access:http://dx.doi.org/10.3779/j.issn.1009-3419.2013.01.05

Internet

http://dx.doi.org/10.3779/j.issn.1009-3419.2013.01.05

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