MOLECULAR MECHANISMS REGULATING LPS-INDUCED INFLAMMATION IN THE BRAIN

Neuro-inflammation, one of the pathogenic causes of neurodegenerative diseases, is regulated through the cholinergic anti-inflammatory pathway via the 7 nicotinic acetylcholine receptor (7 nAChR). We previously showed that either bacterial lipopolysaccharide (LPS) or immunization with the 7(1-208...

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Main Authors: Olena eLykhmus, Nibha eMishra, Lyudmyla eKoval, Olena eKalashnyk, Galyna eGergalova, Kateryna eUspenska, Serghiy eKomisarenko, Hermona eSoreq, Maryna eSkok
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-03-01
Series:Frontiers in Molecular Neuroscience
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Online Access:http://journal.frontiersin.org/Journal/10.3389/fnmol.2016.00019/full