Epigenetic regulation of HIV-1 latency: focus on polycomb group (PcG) proteins
Abstract HIV-1 latency allows the virus to persist until reactivation, in a transcriptionally silent form in its cellular reservoirs despite the presence of effective cART. Such viral persistence represents a major barrier to HIV eradication since treatment interruption leads to rebound plasma virem...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2018-02-01
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Series: | Clinical Epigenetics |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13148-018-0441-z |