Epigenetic regulation of HIV-1 latency: focus on polycomb group (PcG) proteins

Abstract HIV-1 latency allows the virus to persist until reactivation, in a transcriptionally silent form in its cellular reservoirs despite the presence of effective cART. Such viral persistence represents a major barrier to HIV eradication since treatment interruption leads to rebound plasma virem...

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Bibliographic Details
Main Authors: Sheraz Khan, Mazhar Iqbal, Muhammad Tariq, Shahid M. Baig, Wasim Abbas
Format: Article
Language:English
Published: BMC 2018-02-01
Series:Clinical Epigenetics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13148-018-0441-z