Novel 1,2,3-Triazole Derivatives as Mimics of Steroidal System—Synthesis, Crystal Structures Determination, Hirshfeld Surfaces Analysis and Molecular Docking

Novel 1,2,3-Triazole Derivatives as Mimics of Steroidal System—Synthesis, Crystal Structures Determination, Hirshfeld Surfaces Analysis and Molecular Docking

Herein, we present the synthesis and crystal structures determination of five 4-(1-phenyl-1<i>H</i>-1,2,3-triazol-4-yl)phenol derivatives containing halogen atoms, <b>6a</b>–<b>e</b>, which may be used as an excellent mimic of steroids in the drug development proc...

Full description

Bibliographic Details
Main Authors: Mateusz Daśko, Anna Dołęga, Magdalena Siedzielnik, Karol Biernacki, Olga Ciupak, Janusz Rachon, Sebastian Demkowicz
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Molecules
Subjects:
triazoles
hormone analogs
drug design
crystal structures
Hirshfeld surface
molecular docking
Online Access:https://www.mdpi.com/1420-3049/26/13/4059

Internet

https://www.mdpi.com/1420-3049/26/13/4059

Similar Items