The Molecular Biology and Treatment of Malignant Melanoma with BRAFV600 Mutations

Since 2011, the treatment options for metastatic malignant melanoma have significantly changed. In that year, ipilimumab, an anti-CTLA4 monoclonal antibody, and vemurafenib, a potent inhibitor of mutated-BRAF (V600E and V600K), were approved by the U.S. Food and Drug Administration (FDA). In 2013, d...

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Bibliographic Details
Main Author: Michael P. Mullane
Format: Article
Language:English
Published: Aurora Health Care 2014-01-01
Series:Journal of Patient-Centered Research and Reviews
Subjects:
Online Access:http://digitalrepository.aurorahealthcare.org/cgi/viewcontent.cgi?article=1007&context=jpcrr