Development of strategies for SNP detection in RNA-seq data: application to lymphoblastoid cell lines and evaluation using 1000 Genomes data.

Development of strategies for SNP detection in RNA-seq data: application to lymphoblastoid cell lines and evaluation using 1000 Genomes data.

Next-generation RNA sequencing (RNA-seq) maps and analyzes transcriptomes and generates data on sequence variation in expressed genes. There are few reported studies on analysis strategies to maximize the yield of quality RNA-seq SNP data. We evaluated the performance of different SNP-calling method...

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Bibliographic Details
Main Authors: Emma M Quinn, Paul Cormican, Elaine M Kenny, Matthew Hill, Richard Anney, Michael Gill, Aiden P Corvin, Derek W Morris
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3608647?pdf=render

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http://europepmc.org/articles/PMC3608647?pdf=render

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