Accumulation of Uroporphyrin I in Necrotic Tissues of Squamous Cell Carcinoma after Administration of 5-Aminolevulinic Acid

Accumulation of Uroporphyrin I in Necrotic Tissues of Squamous Cell Carcinoma after Administration of 5-Aminolevulinic Acid

5-aminolevulinic acid (5-ALA)-induced protoporphyrin IX (PpIX) fluorescence is widely used for the intraoperative detection of malignant tumors. However, the fluorescence emission profiles of the accompanying necrotic regions of these tumors have yet to be determined. To address this, we performed f...

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Bibliographic Details
Main Authors: Masatomo Beika, Yoshinori Harada, Takeo Minamikawa, Yoshihisa Yamaoka, Noriaki Koizumi, Yasutoshi Murayama, Hirotaka Konishi, Atsushi Shiozaki, Hitoshi Fujiwara, Eigo Otsuji, Tetsuro Takamatsu, Hideo Tanaka
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:International Journal of Molecular Sciences
Subjects:
5-aminolevulinic acid
uroporphyrin I
protoporphyrin IX
tumor necrosis
squamous cell carcinoma
Online Access:https://www.mdpi.com/1422-0067/22/18/10121

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https://www.mdpi.com/1422-0067/22/18/10121

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