Proniosomal gel-derived niosomes: an approach to sustain and improve the ocular delivery of brimonidine tartrate; formulation, in-vitro characterization, and in-vivo pharmacodynamic study

Proniosomal gel-derived niosomes: an approach to sustain and improve the ocular delivery of brimonidine tartrate; formulation, in-vitro characterization, and in-vivo pharmacodynamic study

Brimonidine tartrate (BRT) is a hydrophilic α2 adrenergic agonist used for the treatment of glaucoma. Glaucoma is an ocular disease affecting the anterior segment of the eye requiring lifetime treatment. Owing to the obstacles facing ocular delivery systems and hydrophilicity of BRT, frequent admini...

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Bibliographic Details
Main Authors: Alaa Emad Eldeeb, Salwa Salah, Mahmoud Ghorab
Format: Article
Language:English
Published: Taylor & Francis Group 2019-01-01
Series:Drug Delivery
Subjects:
glaucoma
brimonidine tartrate
sustained ocular delivery
proniosomal gel
tonometer
Online Access:http://dx.doi.org/10.1080/10717544.2019.1609622

Internet

http://dx.doi.org/10.1080/10717544.2019.1609622

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