EspM Is a Conserved Transcription Factor That Regulates Gene Expression in Response to the ESX-1 System

EspM Is a Conserved Transcription Factor That Regulates Gene Expression in Response to the ESX-1 System

Mycobacterial pathogens use the ESX-1 system to transport protein substrates that mediate essential interactions with the host during infection. We previously demonstrated that in addition to transporting proteins, the ESX-1 secretion system regulates gene expression. Here, we identify a conserved t...

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Bibliographic Details
Main Authors: Kevin G. Sanchez, Micah J. Ferrell, Alexandra E. Chirakos, Kathleen R. Nicholson, Robert B. Abramovitch, Matthew M. Champion, Patricia A. Champion
Format: Article
Language:English
Published: American Society for Microbiology 2020-02-01
Series:mBio
Subjects:
esat-6
esx-1
mycobacterium
protein secretion
regulation
feedback control
Online Access:https://doi.org/10.1128/mBio.02807-19

Internet

https://doi.org/10.1128/mBio.02807-19

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