Angiotensin II Receptor Blockers but Not Angiotensin-Converting Enzyme Inhibitors Are Associated With a Reduced Risk of Acute Kidney Injury After Major Surgery

Angiotensin II Receptor Blockers but Not Angiotensin-Converting Enzyme Inhibitors Are Associated With a Reduced Risk of Acute Kidney Injury After Major Surgery

Objective: We investigated the respective effects of preoperative angiotensin-converting-enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs) on the incidence of postoperative acute kidney injury (AKI) and mortality.Methods: In this nested case-control study, we enrolled 20,276 patient...

Full description

Bibliographic Details
Main Authors: Shao-Yu Yang, Tao-Min Huang, Tai-Shuan Lai, Nai-Kuan Chou, Chun-Hao Tsao, Yi-Ping Huang, Shuei-Liong Lin, Yung-Ming Chen, Vin-Cent Wu, NSARF study group
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Pharmacology
Subjects:
angiotensin-converting-enzyme inhibitors
angiotensin receptor blockers
postoperative
acute kidney injury
mortality
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.662301/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.662301/full

Similar Items