In Vitro Analyses of Novel HCN4 Gene Mutations

In Vitro Analyses of Novel HCN4 Gene Mutations

Background/Aims: The hyperpolarization-activated cyclic nucleotide-gated cation channel HCN4 contributes significantly to the generation of basic cardiac electrical activity in the sinus node and is a mediator of modulation by β–adrenergic stimulation. Heterologous expression of sick sinus syndrome...

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Bibliographic Details
Main Authors: Melina Möller, Nicole Silbernagel, Eva Wrobel, Birgit Stallmayer, Elsie Amedonu, Susanne Rinné, Stefan Peischard, Sven G. Meuth, Bernhard Wünsch, Nathalie Strutz-Seebohm, Niels Decher, Eric Schulze-Bahr, Guiscard Seebohm
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-09-01
Series:Cellular Physiology and Biochemistry
Subjects:
Channelopathy
Funny current (If)
Heart
Rhythm
Disease
Bradycardia
Arrhythmias
Pacemaking
HCN Channels
Online Access:https://www.karger.com/Article/FullText/493301

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https://www.karger.com/Article/FullText/493301

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