High CD44 expression mediates p62-associated NFE2L2/NRF2 activation in breast cancer stem cell-like cells: Implications for cancer stem cell resistance

Cluster of differentiation 44 (CD44) is the most common cancer stem cell (CSC) marker and high CD44 expression has been associated with anticancer drug resistance, tumor recurrence, and metastasis. In this study, we aimed to investigate the molecular mechanism by which CD44 and nuclear factor erythr...

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Bibliographic Details
Main Authors: In-geun Ryoo, Bo-hyun Choi, Sae-Kwang Ku, Mi-Kyoung Kwak
Format: Article
Language:English
Published: Elsevier 2018-07-01
Series:Redox Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231718301460