Long Wavelength TCF-Based Fluorescent Probe for the Detection of Alkaline Phosphatase in Live Cells

Long Wavelength TCF-Based Fluorescent Probe for the Detection of Alkaline Phosphatase in Live Cells

A long wavelength TCF-based fluorescent probe (TCF-ALP) was developed for the detection of alkaline phosphatase (ALP). ALP-mediated hydrolysis of the phosphate group of TCF-ALP resulted in a significant fluorescence “turn on” (58-fold), which was accompanied by a colorimetric response from yellow to...

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Bibliographic Details
Main Authors: Lauren Gwynne, Adam C. Sedgwick, Jordan E. Gardiner, George T. Williams, Gyoungmi Kim, John P. Lowe, Jean-Yves Maillard, A. Toby A. Jenkins, Steven D. Bull, Jonathan L. Sessler, Juyoung Yoon, Tony D. James
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Chemistry
Subjects:
reaction-based fluorescent probe
alkaline phosphatase
cell imaging
fluorescence
colorimetric
Online Access:https://www.frontiersin.org/article/10.3389/fchem.2019.00255/full

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https://www.frontiersin.org/article/10.3389/fchem.2019.00255/full

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