Poly r(C) Binding Protein-1 is Central to Maintenance of Cancer Stem Cells in Prostate Cancer Cells

Poly r(C) Binding Protein-1 is Central to Maintenance of Cancer Stem Cells in Prostate Cancer Cells

Aims: To investigate global proteomic changes induced in CD44+CD24- stem cells isolated from the prostate cancer cell lines, LNCaP and DU145, post prolonged TGF-β treatment in order to understand underlying mechanisms that promote stemness in prostate cancer cells. Methods: CD44+CD133+α2β1Integrin+C...

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Bibliographic Details
Main Authors: Qi Chen, Zhi-kang Cai, Yan-bo Chen, Meng Gu, Da-chao Zheng, Juan Zhou, Zhong Wang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2015-02-01
Series:Cellular Physiology and Biochemistry
Subjects:
Prostate cancer
Poly r(C) binding protein-1
PCBP1
Stemness
Metastasis
Cancer stem cells
Online Access:http://www.karger.com/Article/FullText/373931

Internet

http://www.karger.com/Article/FullText/373931

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