Engineered Biosynthesis of Alkyne-Tagged Polyketides by Type I PKSs
Summary: Polyketides produced by modular polyketide synthases (PKSs) are important small molecules widely used as drugs, pesticides, and biological probes. Tagging these polyketides with a clickable functionality enables the visualization, diversification, and mode of action study through bio-orthog...
Main Authors: | William B. Porterfield, Nannalin Poenateetai, Wenjun Zhang |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2020-03-01
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Series: | iScience |
Online Access: | http://www.sciencedirect.com/science/article/pii/S258900422030122X |
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