Experimental meningococcal sepsis in congenic transgenic mice expressing human transferrin.

Severe meningococcal sepsis is still of high morbidity and mortality. Its management may be improved by an experimental model allowing better understanding of its pathophysiology. We developed an animal model of meningococcal sepsis in transgenic BALB/c mice expressing human transferrin. We studied...

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Bibliographic Details
Main Authors: Marek Szatanik, Eva Hong, Corinne Ruckly, Morgan Ledroit, Dario Giorgini, Katarzyna Jopek, Marie-Anne Nicola, Ala-Eddine Deghmane, Muhamed-Kheir Taha
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3141004?pdf=render