Protein Tyrosine Phosphatase 1B Inhibition and Glucose Uptake Potentials of Mulberrofuran G, Albanol B, and Kuwanon G from Root Bark of Morus alba L. in Insulin-Resistant HepG2 Cells: An In Vitro and In Silico Study

Protein Tyrosine Phosphatase 1B Inhibition and Glucose Uptake Potentials of Mulberrofuran G, Albanol B, and Kuwanon G from Root Bark of Morus alba L. in Insulin-Resistant HepG2 Cells: An In Vitro and In Silico Study

Type II diabetes mellitus (T2DM) is the most common form of diabetes and has become a major health problem across the world. The root bark of Morus alba L. is widely used in Traditional Chinese Medicine for treatment and management of diabetes. The aim of the present study was to evaluate the enzyme...

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Bibliographic Details
Main Authors: Pradeep Paudel, Ting Yu, Su Hui Seong, Eun Bi Kuk, Hyun Ah Jung, Jae Sue Choi
Format: Article
Language:English
Published: MDPI AG 2018-05-01
Series:International Journal of Molecular Sciences
Subjects:
Morus alba L.
root bark
protein tyrosine phosphatase 1B
α-Glucosidase
molecular docking
insulin-resistant HepG2
Online Access:http://www.mdpi.com/1422-0067/19/5/1542

Internet

http://www.mdpi.com/1422-0067/19/5/1542

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