The RNA-binding protein YBX1 regulates epidermal progenitors at a posttranscriptional level
The integrity of the stratified epithelia relies on controlled cell turnover but it is unclear how mRNA binding proteins regulates this. Here, the authors show that the RNA binding protein Y-box binding protein-1 translationally represses cytokines, so preventing senescence and maintaining epidermal...
Main Authors: | Eunjeong Kwon, Kristina Todorova, Jun Wang, Rastislav Horos, Kevin K. Lee, Victor A. Neel, Gian Luca Negri, Poul H. Sorensen, Sam W. Lee, Matthias W. Hentze, Anna Mandinova |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2018-04-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-018-04092-0 |
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