The RNA-binding protein YBX1 regulates epidermal progenitors at a posttranscriptional level

The RNA-binding protein YBX1 regulates epidermal progenitors at a posttranscriptional level

The integrity of the stratified epithelia relies on controlled cell turnover but it is unclear how mRNA binding proteins regulates this. Here, the authors show that the RNA binding protein Y-box binding protein-1 translationally represses cytokines, so preventing senescence and maintaining epidermal...

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Bibliographic Details
Main Authors: Eunjeong Kwon, Kristina Todorova, Jun Wang, Rastislav Horos, Kevin K. Lee, Victor A. Neel, Gian Luca Negri, Poul H. Sorensen, Sam W. Lee, Matthias W. Hentze, Anna Mandinova
Format: Article
Language:English
Published: Nature Publishing Group 2018-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-04092-0

Internet

https://doi.org/10.1038/s41467-018-04092-0

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