Targeting PML-RARα and Oncogenic Signaling Pathways by Chinese Herbal Mixture Tien-Hsien Liquid in Acute Promyelocytic Leukemia NB4 Cells

Tien-Hsien Liquid (THL) is a Chinese herbal mixture that has been used worldwide as complementary treatment for cancer patients in the past decade. Recently, THL has been shown to induce apoptosis in various types of solid tumor cells in vitro. However, the underlying molecular mechanisms have not y...

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Bibliographic Details
Main Authors: Chih-Jung Yao, Chia-Ming Yang, Shuang-En Chuang, Jiann-Long Yan, Chun-Yen Liu, Suz-Wen Chen, Kun-Huang Yan, Tung-Yuan Lai, Gi-Ming Lai
Format: Article
Language:English
Published: Hindawi Limited 2011-01-01
Series:Evidence-Based Complementary and Alternative Medicine
Online Access:http://dx.doi.org/10.1093/ecam/nep165