Imbalance of Drug Transporter-CYP450s Interplay by Diabetes and Its Clinical Significance

The<b> </b>pharmacokinetics of a drug is dependent upon the coordinate work of influx transporters, enzymes and efflux transporters (i.e., transporter-enzyme interplay). The transporter–enzyme interplay may occur in liver, kidney and intestine. The influx transporters involving drug tran...

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Bibliographic Details
Main Authors: Yiting Yang, Xiaodong Liu
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Pharmaceutics
Subjects:
Online Access:https://www.mdpi.com/1999-4923/12/4/348