ERAP1 overexpression in HPV-induced malignancies: A possible novel immune evasion mechanism

ERAP1 overexpression in HPV-induced malignancies: A possible novel immune evasion mechanism

Immune evasion of tumors poses a major challenge for immunotherapy. For human papillomavirus (HPV)-induced malignancies, multiple immune evasion mechanisms have been described, including altered expression of antigen processing machinery (APM) components. These changes can directly influence epitope...

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Bibliographic Details
Main Authors: Alina Steinbach, Jan Winter, Miriam Reuschenbach, Renata Blatnik, Alexandra Klevenz, Miriam Bertrand, Stephanie Hoppe, Magnus von Knebel Doeberitz, Agnieszka K. Grabowska, Angelika B. Riemer
Format: Article
Language:English
Published: Taylor & Francis Group 2017-07-01
Series:OncoImmunology
Subjects:
antigen processing machinery (apm)
cervical cancer
endoplasmic reticulum aminopeptidase 1 (erap1)
human papillomavirus (hpv)
t-cell epitopes
Online Access:http://dx.doi.org/10.1080/2162402X.2017.1336594

Internet

http://dx.doi.org/10.1080/2162402X.2017.1336594

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