Lumican - derived peptides inhibit melanoma cell growth and migration.

Lumican, a small leucine-rich proteoglycan of the extracellular matrix, presents potent anti-tumor properties. Previous works from our group showed that lumican inhibited melanoma cell migration and tumor growth in vitro and in vivo. Melanoma cells adhered to lumican, resulting in a remodeling of th...

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Bibliographic Details
Main Authors: Katarzyna Pietraszek, Stéphane Brézillon, Corinne Perreau, Maria Malicka-Błaszkiewicz, François-Xavier Maquart, Yanusz Wegrowski
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3788744?pdf=render